NMR studies of pH-dependent conformational polymorphism of alternating (C-T)n sequences
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چکیده
منابع مشابه
NMR studies of pH-dependent conformational polymorphism of alternating (C-T)n sequences.
Alternating (C-T)n sequences are involved in the H-DNA structure associated with (GA)n.(CT)n sequences. Low pH values facilitate H-DNA formation. We have undertaken a detailed analysis of the structural consequences of the (C-T)n sequence as a function of pH. The structures of three DNA oligonucleotides, d(CT)4, d(TC)4 and d(TC)15, have been studied by NMR. We found that their conformations are...
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1 Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russia, Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russia, 3 Institute of Organic Chemistry, Karlsruhe Institute of Technology, Karlsruhe, Germany, 4 Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany, 5 Institute of Physiologic...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1993
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/21.16.3839